SalivaDirect: A simplified and flexible platform to enhance SARS-CoV-2 testing capacity

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Yale SARS-CoV-2 Surveillance Initiatives

We’re using a variety of tools, including viral sequencing, wastewater surveillance, and saliva-based assays, to uncover how SARS-CoV-2 is spreading in Connecticut and beyond.

Genomic epidemiology to track SARS-CoV-2

Back to our regular programing…

Yale School of Public Health

The Grubaugh Lab is located within the Yale School of Public Health, Department of Epidemiology of Microbial Diseases. Our department uniquely combines clinical, computational, and laboratory-based approaches to combat infectious diseases around the world.

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Genomics to study virus emergence

We are using pathogen genomics to study how mosquito- and tick-borne viruses, like Zika, West Nile, chikungunya, and Powassan emerge into new areas, cause disease, and adapt to novel environments. Ultimately, our goal is to better understand and respond to outbreaks.

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Novel methods to detect oubreaks

WestNile 4K Project

By partnering with Kristian Andersen, Ryan Smith, and 40+ surveillance labs from across the country, we are planning to sequence more than 4,000 virus genomes to reconstruct a high definition picture of West Nile virus spread and evolution during the last 20 years in the United States. The data that we generate will be immediately released and, along with other entomological data, will be used to uncover local transmission dynamics. 

see our progress

Rapid data sharing using Nextstrain

Nextstrain is an open-source project created by Trevor Bedford and Richer Neher to harness the scientific and public health potential of pathogen genome data. We recently teamed up with the Nextstrain team, including James Hadfield, to create a portal to visualize West Nile virus spread and evolution during the last 20 years in North America. We also create “community” pages to share ongoing data analysis with our collaborators and the public.

see Nextstrain in action
Want to join the fun?

We are always looking for talented scientists to join the group.

Job posting
Open science

We’ll make our data and protocols available as they are generated.

data and protocols
If you like the art…

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steampunk phage

The latest from New Haven…

Want to join?

Updated 2020.08.10 We are currently seeking a postdoc for our SalivaDirect team. Please see the posting on our CovidTrackCT website. ~Cheers!

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2020 opportunities for MPH students

Currently our lab does not have any paid technician positions for new students, but we are open to help host 1 or 2 students currently enrolled in the MPH program[…]

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Márcio the MinION Master

**One of our primary missions is to provide training for researches on how to sequence viruses and analyze genetic data. We either bring students to our lab for internships or[…]

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