SalivaDirect: A simplified and flexible platform to enhance SARS-CoV-2 testing capacity
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Yale SARS-CoV-2 Surveillance Initiatives
We’re using a variety of tools, including viral sequencing, wastewater surveillance, and saliva-based assays, to uncover how SARS-CoV-2 is spreading in Connecticut and beyond.
Genomic epidemiology to track SARS-CoV-2
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Yale School of Public Health
The Grubaugh Lab is located within the Yale School of Public Health, Department of Epidemiology of Microbial Diseases. Our department uniquely combines clinical, computational, and laboratory-based approaches to combat infectious diseases around the world.
read more about our departmentGenomics to study virus emergence
We are using pathogen genomics to study how mosquito- and tick-borne viruses, like Zika, West Nile, chikungunya, and Powassan emerge into new areas, cause disease, and adapt to novel environments. Ultimately, our goal is to better understand and respond to outbreaks.
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Novel methods to detect oubreaks
WestNile 4K Project
By partnering with Kristian Andersen, Ryan Smith, and 40+ surveillance labs from across the country, we are planning to sequence more than 4,000 virus genomes to reconstruct a high definition picture of West Nile virus spread and evolution during the last 20 years in the United States. The data that we generate will be immediately released and, along with other entomological data, will be used to uncover local transmission dynamics.
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Rapid data sharing using Nextstrain
Nextstrain is an open-source project created by Trevor Bedford and Richer Neher to harness the scientific and public health potential of pathogen genome data. We recently teamed up with the Nextstrain team, including James Hadfield, to create a portal to visualize West Nile virus spread and evolution during the last 20 years in North America. We also create “community” pages to share ongoing data analysis with our collaborators and the public.
see Nextstrain in actionThe latest from New Haven…
Teaming up with the NBA
In June 2020, we formed a collaboration with the National Basketball Association (NBA) and the Players Association (NBPA) to develop a new saliva-based SARS-CoV-2 test (SalivaDirect) and to uncover key[…]
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Tracking COVID-19 outbreaks in the NFL
An interview with Joseph Fauver by the Wall Street Journal outlines how we used genomic sequencing to track the spread of SARS-CoV-2 in NFL facilities. Article: Decoding an Outbreak: How[…]
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