Yale School of Public Health

The Grubaugh Lab is located within the Yale School of Public Health, Department of Epidemiology of Microbial Diseases. Our department uniquely combines clinical, computational, and laboratory-based approaches to combat infectious diseases around the world.

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Genomics to study virus emergence

We are using pathogen genomics to study how mosquito- and tick-borne viruses, like Zika, West Nile, chikungunya, and Powassan emerge into new areas, cause disease, and adapt to novel environments. Ultimately, our goal is to better understand and respond to outbreaks.

learn more about our research

Novel methods to detect oubreaks

West Nile virus Nextstrain

Nextstrain is an open-source project created by Trevor Bedford and Richer Neher to harness the scientific and public health potential of pathogen genome data. We recently teamed up with the Nextstrain team, including James Hadfield, to create a portal to visualize West Nile virus spread and evolution during the last 20 years in North America. We will continually update this site with publicly available data to provide teaching and research tools, as well as improve our outbreak response capabilities.

see Nextstrain in action

WestNile 4K Project

By partnering with Kristian Andersen, Ryan Smith, and 40+ surveillance labs from across the country, we are planning to sequence more than 4,000 virus genomes to reconstruct a high definition picture of West Nile virus spread and evolution during the last 20 years in the United States. The data that we generate will be immediately released and, along with other entomological data, will be used to uncover local transmission dynamics. 

see our progress

The latest from New Haven…

Márcio the MinION Master

**One of our primary missions is to provide training for researches on how to sequence viruses and analyze genetic data. We either bring students to our lab for internships or[…]

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White Tears: Chronic Lyme Disease

In today’s news, the lines between fact and fiction are blurred, leaving people susceptible to false claims, ideas, and opinions. The power to craft these narratives lies in the hands[…]

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Study WNV? We need your help!

Update: The project now has a website – WestNile4k.org/ If you do West Nile virus (WNV) surveillance or have a freezer full of old field-collected WNV samples, we need your help.[…]

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Want to join the fun?

We are always looking for talented scientists to join the group.

Job posting
Open science

We’ll make our data and protocols available as they are generated.

data and protocols
If you like the art…

Find more online

steampunk phage